Table 2.
Medication use in patients with UC vs IPAA
| Medication Class | UC N=128 (%) | IPAA N=94 (%) | p-value | ||
|---|---|---|---|---|---|
|
| |||||
| UC | PRE-STC | POST-IPAA | * | ** | |
| None | 6 (4.7) | 0 (0) | 40 (43.0) | .08 | <.001 |
|
| |||||
| Mesalamine | 68 (53.1) | 52 (61.2) | 6 (6.5) | .31 | <.001 |
|
| |||||
| Immunomodulators | 21 (16.4) | 27 (31.8) | 3 (3.2) | .01 | .002 |
|
| |||||
| Steroids | 28 (21.9) | 45 (52.9) | 13 (14.0) | <.001 | .19 |
|
| |||||
| Antibiotics | - | 12 (14.1) | 11 (12.9) | - | - |
|
| |||||
| Biologics | |||||
| Anti-TNFs | 45 (35.2) | 47 (55.3) | 15 (16.1) | .01 | .003 |
| Anti-integrin | 22 (17.2) | 15 (17.6) | 5 (5.4) | 1.0 | .01 |
| Anti-interleukin | 1 (0.8) | 0 (0) | 13 (14.0) | 1.0 | <.001 |
*
P value between UC and IPAA pre subtotal colectomy (STC)
**
P-value between UC and post-IPAA at the time of IBD-DI