Table 1. Demographic and clinicopathologic characteristics of 103 patients with papillary thyroid microcarcinoma, stratified by BRAF genotype.
| Characteristic | Mutant BRAF (n=72) | Wild-type BRAF (n=31) | P |
|---|---|---|---|
| Sex | 0.445 | ||
| Male | 19 (26.39) | 6 (19.35) | |
| Female | 53 (73.61) | 25 (80.65) | |
| Age, years | |||
| Mean ± SD (range) | 43.69±12.30 (26–78) | 44.58±9.57 (32–66) | 0.433* |
| <50 | 63 (70.79) | 26 (72.22) | 0.219** |
| ≥50 | 26 (29.21) | 10 (27.78) | |
| Tumor size (cm) | |||
| Mean ± SD (range) | 0.71±0.17 (0.30–1.00) | 0.64±0.18 (0.35–1.00) | 0.042* |
| ≤0.5 | 13 (18.06) | 13 (41.94) | 0.010** |
| >0.5 | 59 (81.94) | 18 (68.06) | |
| ACR TI-RADS score | |||
| Mean ± SD (range) | 9.46±1.87 (6–13) | 10.03±1.68 (7–12) | 0.133* |
| <7 | 5 (6.94) | 0 (0.00) | |
| ≥7 | 67 (83.06) | 31 (1.00) | |
| Bethesda stage | 0.001** | ||
| I | 1 (1.39) | 0 (0.00) | |
| III | 2 (2.78) | 1 (3.23) | |
| IV | 1 (1.39) | 0 (0.00) | |
| V | 9 (12.50) | 16 (51.61) | |
| VI | 59 (81.94) | 14 (45.16) |
Values are displayed as n (%), unless otherwise noted. *, Wilcoxon rank sum test; **, Chi-squared test. SD, standard deviation; ACR, American College of Radiology; TI-RADS, thyroid imaging, reporting and data system.