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. 2022 Sep 12;23(11):e54686. doi: 10.15252/embr.202254686

Figure 3. YTHDC1 is pre‐loaded to RNA Pol II with MTC by interacting with WTAP.

Figure 3

  • A–C
    The Co‐IP results of endogenous WTAP, METTL3 and METTL14 with YTHDC1. The endogenous WTAP and YTHDC1 can be pulled down reciprocally by each other in the presence of RNase A.
  • D
    The Co‐IP results of Myc‐CBLL1, Myc‐RBM15, Myc‐ZC3H13 and Myc‐VIRMA with Endogenous YTHDC1. None of them can pull down Endogenous YTHDC1 in the presence of RNase A.
  • E
    Endogenous YTHDC1 interacts with RPB3 in a RNA independent way.

Source data are available online for this figure.