Figure EV5. Higher m⁶A levels in the proximal poly(A) sites correlates with genes with more proximal poly(A) sites usage after knockdown of YTHDC1.

• A, B
  m⁶A peak density near APA sites and stop codon in (A and B), respectively. Genes with shortened 3′ UTR show a higher m⁶A modification near of the proximal APA sites compared with genes with lengthened 3′ UTR or background. But shortened 3′ UTR near of the stop codon did not show enriched m⁶A modification than mRNA with lengthened 3′ UTR or background. The density of m⁶A peak was calculated as the number of peak in a 10‐nt interval divided by the total number of mRNAs that contained this position.