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. 2022 Oct 16;50(19):10817–10838. doi: 10.1093/nar/gkac866

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© The Author(s) 2022. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 1. — A mechanism for the formation of nucleic-acid-based condensates. (A) Monolayer FUS recruitment on DNA (57). (B) FUS interaction with PAR and formation of compartments, concentrating PAR, FUS and damaged DNA (5,6,59).