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Reaction conditions: carboxylic acid (2 mmol), 25% ammonia solution (2.4 mmol), aldehyde (2 mmol), isocyanide (2 mmol), TFE (2 mL), 60 °C, overnight.
Yield refers to the purified products.
Published Ugi adducts from our previous articles.
New synthesized Ugi adducts in this work.
