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. 2022 Oct 6;26(21):5414–5425. doi: 10.1111/jcmm.17564

FIGURE 3.

FIGURE 3

ECH reduced caspase‐1 mediated pyroptosis and ASC speckles in primary cardiomyocytes of neonatal rat induced by ISO. (A) Representative flow cytometry image of caspase‐1 mediated pyroptosis in Ctrl, ISO and ECH‐treated cardiomyocytes. (B) Representative immunofluorescence staining image of ASC in Ctrl, ISO and ECH‐treated cardiomyocytes. (C) Statistical histogram of cardiomyocyte pyroptotic rate mediated by caspase‐1. (D) Statistical histogram of ASC speckles positive rate of cardiomyocytes. All *p < 0.05 versus Ctrl, **p < 0.01 versus Ctrl; #p < 0.05 versus ISO, ##p < 0.01 versus ISO. Error bars represent SD.