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Most frequent comorbidities at the start and at the end of the study period
| Most frequent comorbidity | 2000–2003 | 2017–2021 |
| 1 | Osteoarthritis | Hypertension |
| 2 | Hypertension | Osteoarthritis |
| 3 | Lipid metabolism disorder | Lipid metabolism disorder |
| 4 | Malignancy | Diabetes mellitus |
| 5 | Atherosclerosis | Atherosclerosis |
