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. 2022 Nov 2;10(11):e005414. doi: 10.1136/jitc-2022-005414

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© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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Mean per cent change in tumor diameter as a function of the time after the beginning of treatment for virtual patients. Simulations were grouped according to RECIST criteria; progressive disease (PD; x>20%; red), stable disease (SD; −30%≤x ≤ 20%; yellow), partial response (PR; x < −30%; cyan), and complete response (CR; x = −100%; green). Shaded regions correspond to the 95% CI of the simulations in the corresponding RECIST category. RECIST, Response Evaluation Criteria in Solid Tumors.