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Effects of ShlA and VacA on epithelial cells
| Effect of toxin action | Characteristic for:
|
|
|---|---|---|
| ShlA | VacA | |
| Toxin aggregation | Yes | Yes |
| Activity half-life at room temperature | 3 min | Stable |
| Induction of vacuolation reversible by bafilomycin A1 | No | Yes |
| Reversion of formed vacuoles by bafilomycin A1 | No | Yes |
| Neutral red-stainable vacuoles | No | Yes |
| Lysis of target cells | Yes | No |
