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Complement-based therapies currently under trial for MN.
| Name of drug | Target | Phase of development |
|---|---|---|
| BCX9930 | Factor D | Phase II (NCT05162066) |
| Eculizumab | C5 | Aborted |
| Iptacopan (LNP023) | Factor B | Phase II (NCT04154787) |
| Narsoplimab (OMS721) | MASP2 | Phase II (NCT02682407) |
| Pegcetacoplan (APL-2) | C3, C3b | Aborted |
