Figure 8.

Effect of 1G3E5 administered after the induction of LPS-induced pulmonary inflammation in deer mice (P. maniculatus)

Animals received 2.5 mg LPS via a nebulizer and 24 h later received either IgG or 1G3E5. Animals were sacrificed 24 h later and lung histology was evaluated.

(A) Representative microphotographs of H&E-stained sections of lungs of animals that received LPS + IgG or LPS+1G3E5 (scale bar: 25 uM).

(B) Scoring of inflammation was evaluated histologically (n = 6 per group). Results were analyzed by the Mann Whitney U test.