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. 2022 Nov 7;10(12):e734. doi: 10.1002/iid3.734

Figure 1.

Figure 1

The pathological changes of psoriasis induced by IMQ in mice. (A/B/C/D) The skin changes of mice (Control, Model, Etanercept (0.1 mg/ml), Etanercept (0.2 mg/ml) and Etanercept (0.4 mg/ml) groups) recorded by PASI scores. (E) The skin changes of mice detected by H&E staining (×400). Scale bar = 50 μm. (F) The changes of epidermal thickness were measured by the image analysis system. *p < .05 compared with Control group; #p < .05 compared with Model group. IMQ, imiquimod; PASI, Psoriasis area and severity index.