Table 2.
Vaccination responses in the QIV and ATIV cohorts.
| VIRUS | POST-VACCINE | QIV | ATIV | P-value |
|---|---|---|---|---|
| Wt H1 | GMTs (CI 95%) | 116.6 (79.9–170.1) | 74.5 (58.2–95.3) | .053 |
| SPR (%) | 89.1 | 79.3 | .142 | |
| Fold induction | 3.5 | 2.8 | .218 | |
| SCR (%) | 41.3 | 33.6 | .358 | |
| H1-ΔSb | GMTs (CI 95%) | 10.3 (7.5–14.2) | 8.1 (7.0–9.3) | .105 |
| SPR (%) | 23.9 | 7.8 | .005** | |
| Fold induction | 1.6 | 1.3 | .043* | |
| SCR (%) | 17.4 | 9.5 | .158 | |
| H1-ΔSa | GMTs (CI 95%) | 111.4 (72.7–170.8) | 48.7 (37.3–63.6) | <.001*** |
| SPR (%) | 80.4 | 66.4 | .077 | |
| Fold induction | 3.9 | 2.4 | .007** | |
| SCR (%) | 43.5 | 33.6 | .240 | |
| H1-ΔCb | GMTs (CI 95%) | 87.6 (59.2–129.6) | 55.6 (44.1–69.9) | .042* |
| SPR (%) | 80.4 | 75.0 | .462 | |
| Fold induction | 3.3 | 2.3 | .043* | |
| SCR (%) | 41.3 | 31.9 | .256 | |
| H1-ΔCa1 | GMTs (CI 95%) | 113.1 (75.0–170.7) | 58.6 (46.3–74.3) | .005** |
| SPR (%) | 84.8 | 75.9 | .213 | |
| Fold induction | 3.4 | 2.5 | .089 | |
| SCR (%) | 34.8 | 29.3 | .497 | |
| H1-ΔCa2 | GMTs (CI 95%) | 35.5 (22.6–55.6) | 32.3 (25.9–40.2) | .675 |
| SPR (%) | 52.2 | 56.9 | .585 | |
| Fold induction | 2.3 | 2.0 | .515 | |
| SCR (%) | 21.7 | 21.6 | .275 |
P-values were determined with the Student T-test for GMT and Fold-induction and chi-square test for SPR and SCR. *P < .05, **P < .01, ***P < .001.