Table 1.
Reference values controls | Alzheimer's dementia | Dementia with Lewy bodies | Fronto‐temporal dementia | Multiple Sclerosis | |
---|---|---|---|---|---|
N | 833 | 293 | 124 | 373 | 75 |
Age, years mean ± SD | 54 ± 14 | 64 ± 8 | 69 ± 7 | 63 ± 8 | 46 ± 9 |
Age, years range | 19–85 | 37–81 | 52–85 | 26–87 | 25–68 |
Female, N (%) | 408 (49%) | 156 (53%) | 12 (10%) | 161 (43%) | 36 (48%) |
Blood NfL, pg/mL mean ± SD | 10 ± 7 | 19 ± 12 | 20 ± 18 | 39 ± 57 | 11 ± 12 |
Blood NfL, pg/mL range | 2–113 | 5–123 | 5–160 | 2–608 | 2–69 |
CSF NfL, pg/mL mean ± SD | 723 ± 500 | 1337 ± 1108 | 1270 ± 1106 | 3137 ± 2393 | 1579 ± 2213 |
CSF NfL, pg/mL range | 157–4722 | 189–13,111 | 183–7499 | 548–17,925 | 465–17,558 |
SD, standard deviation; NfL, Neurofilament light chain; Blood, EDTAplasma or serum; CSF, cerebrospinal fluid.