Table 2.

Mixed model for the global cognitive composite in the limited dataset (≤6 years of follow‐up) as predicted by CSF Aβ42/Aβ40. Age and CSF Aβ42/Aβ40 were standardized.

Predictors	Estimates	Std. Error	df	CI	p
(Intercept)	−0.829	0.206	370.515	−1.234 to −0.424	<0.001
Age [Years]	−0.199	0.032	370.538	−0.262 to −0.137	<0.001
Education [Years]	0.047	0.012	370.605	0.023 to 0.070	<0.001
Race [Black]	−0.594	0.107	374.482	−0.804 to −0.384	<0.001
APOE ε4 status (ε4 carrier)	0.064	0.069	370.709	−0.072 to 0.200	0.353
Sex [Female]	0.292	0.061	370.706	0.171 to 0.412	<0.001
Time	−0.020	0.006	251.317	−0.032 to −0.008	0.001
CSF Aβ42/Aβ40	0.094	0.034	370.668	0.027 to 0.161	0.006
Time * CSF Aβ42/Aβ40	0.020	0.006	260.175	0.008 to 0.032	0.001
Random effects
σ2	0.06
τ00 id	0.30
τ11 id.time	0.01
ρ01 id	0.17
ICC	0.86
N id	371
Observations	1637
Marginal R2/Conditional R2	0.203/0.887