Table 3.

Mixed model for the global cognitive composite in the limited dataset (≤6 years of follow‐up) as predicted by plasma Aβ42/Aβ40. Age and plasma Aβ42/Aβ40 were standardized.

Predictors	Estimates	Std. Error	df	CI	p
(Intercept)	−0.816	0.208	370.479	−1.225 to −0.408	<0.001
Age [Years]	−0.216	0.031	370.833	−0.277 to −0.155	<0.001
Education [Years]	0.048	0.012	370.596	0.024 to 0.071	<0.001
Race [Black]	−0.583	0.108	374.460	−0.796 to −0.370	<0.001
APOE ε4 status (ε4 carrier)	0.011	0.066	370.815	−0.119 to 0.141	0.868
Sex [Female]	0.267	0.062	370.724	0.144 to 0.389	<0.001
Time	−0.021	0.006	247.306	−0.033 to −0.008	0.001
Plasma Aβ42/Aβ40	0.052	0.033	369.660	−0.012 to 0.116	0.114
Time * Plasma Aβ42/Aβ40	0.014	0.006	240.178	0.002 to 0.026	0.021
Random effects
σ2	0.06
τ00 id	0.30
τ11 id.time	0.01
ρ01 id	0.18
ICC	0.86
N id	371
Observations	1637
Marginal R2/Conditional R2	0.186/0.886