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. 2022 Nov 8;12:05038. doi: 10.7189/jogh.12.05038

Table 3.

Lethality comparison between waves and the interwave period among hospitalized patients with COVID-19

Age group Comorbidities CFR-interwave CFR-waves Difference-CFR Fisher exact test FDR*
20,39
None
7.91
11.65
3.74
1.42x10-5
20,39
Obes
13.00
18.21
5.21
1.50x10-2
20,39
DM, AHP
16.07
32.55
16.48
3.37x10-2
20,39
DM, Obes
13.46
28.76
15.30
4.48x10-2
40,59
None
20.37
29.72
9.34
2.29x10-27
40,59
Obes
22.35
33.79
11.45
1.30x10-11
40,59
DM, AHP, Obes
27.72
42.02
14.30
1.65x10-6
40,59
AHP
25.57
35.33
9.76
2.35x10-6
40,59
DM, AHP
32.86
42.33
9.47
2.35x10-6
40,59
AHP, Obes
26.04
37.69
11.64
5.00x10-5
40,59
DM
30.10
38.08
7.98
6.81x10-5
40,59
DM, Obes
26.72
38.52
11.80
1.20x10-3
40,59
Other
24.36
29.15
4.79
2.51x10-2
60,79
None
40.85
49.89
9.04
8.82x10-16
60,79
DM
41.51
53.41
11.90
3.35x10-10
60,79
AHP
41.01
50.55
9.54
3.64x10-9
60,79
Obes
39.41
52.80
13.39
2.35x10-6
60,79
DM, AHP
46.79
53.64
6.84
2.35x10-6
60,79
Other
39.07
47.82
8.75
1.02x10-4
60,79
DM, AHP, Obes
45.36
54.21
8.85
4.10x10-4
60,79
DM, Obes
39.81
54.26
14.45
7.39x10-4
60,79
AHP, Obes
46.10
52.27
6.16
4.48x10-2
80+
None
50.47
59.02
8.55
8.76x10-4
80+ DM, AHP 51.75 58.02 6.27 4.48x10-2

DM – diabetes mellitus, AHP – arterial hypertension, Obes – obesity, CFR-wave – cases occurred in either peak, Difference-CFR – the difference between CFR-wave and CFR-interwave, CFR-interwave – cases occurred during the period interpeak, FDR – Fisher exact test

*Fisher exact test with Benjamini-Hochberg (BH) correction was used to estimate difference. FDR<0.05 – statistically significant value.