Table 1.

Mutation rate analysis.

Genotype	Strain	hom3-10 reversion rate*	lys2-10A reversion rate*	CanR forward mutation rate*
Wild-type	RDKY5964	1.77 [0.79–4.32] ×10−9 (1)	5.94 [1.31–13.6] ×10−9 (1)	5.26 [3.93–7.62] ×10−8 (1)
msh2Δ	RDKY9658	4.20 [3.39–7.87] ×10−6 (2373)	1.36 [1.24–4.65] ×10−4 (22,896)	2.04 [1.56–4.22] ×10−6 (39)
mlh1Δ	RDKY9670	4.17 [3.30–6.95] ×10−6 (2356)	1.42 [1.10–1.59] ×10−4 (23,906)	2.24 [1.77–5.42] ×10−6 (43)
pms1Δ	RDKY9673	4.70 [3.14–7.23] ×10−6 (2655)	9.43 [7.33–11.7] ×10−5 (15,875)	2.59 [2.35–3.74] ×10−6 (49)
mlh1-Q57L,T59L	RDKY9789	3.33 [2.29–3.84] ×10−6 (1881)	9.23 [5.35–13.2] ×10−5 (15,539)	1.81 [1.27–3.70] ×10−6 (34)
mlh1-K5KC	RDKY9792	4.89 [4.08–9.28] ×10−8 (28)	2.88 [2.18–3.89] ×10−6 (485)	1.24 [0.97–1.98] ×10−7 (2)

^*95% confidence intervals in brackets [], fold change over wild-type in parentheses ().