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Schematic summarizing increased senescent-associated markers and extracellular matrix (ECM) in aging airways, exacerbated in asthma in the elderly (AIE). ASM, airway smooth muscle; SA-Gal, senescence-associated β-galactosidase; SASP, senescence-associated secretory phenotype; TAF, telomere-associated foci. [Image created with BioRender.com and published with permission.]
