Table 3.
Odds of Myocarditis/Pericarditis 21 Days After Second Dose of COVID-19 mRNA Vaccination (mRNA-1273 vs BNT162b2)
| Myocarditis |
Pericarditis |
Myopericarditis |
||||
|---|---|---|---|---|---|---|
| Crude OR (95% CI) | Adjusted OR (95% CI)a | Crude OR (95% CI) | Adjusted OR (95% CI) | Crude OR (95% CI) | Adjusted OR (95% CI) | |
| Overall | 2.82 (1.69-4.71) | 2.78 (1.67-4.62) | 2.42 (1.32-4.48) | 2.42 (1.31-4.46) | 2.66 (1.78-3.97) | 2.63 (1.76-3.93) |
| Sex | ||||||
| Men | 3.16 (1.74-5.73) | 3.21 (1.77-5.83) | 2.08 (0.99-4.37) | 2.12 (1.01-4.46) | 2.70 (1.67-4.34) | 2.77 (1.72-4.48) |
| Women | 1.79 (0.64-5.05) | 1.82 (0.65-5.12) | 3.14 (1.06-9.36) | 3.21 (1.07-9.54) | 2.34 (1.11-4.91) | 2.40 (1.14-5.05) |
| Age, y | ||||||
| 18-39 | 5.24 (2.76-9.95) | 5.09 (2.68-9.66) | 2.24 (1.04-4.85) | 2.21 (1.02-4.78) | 3.83 (2.32-6.30) | 3.74 (2.27-6.16) |
| ≥40 | 0.54 (0.15-1.87) | 0.52 (0.15-1.82) | 2.87 (1.04-7.93) | 2.83 (1.02-7.79) | 1.32 (0.63-2.73) | 1.29 (0.62-2.67) |
Each OR represents the odds of the outcome among mRNA-1273 relative to BNT162b2, and therefore, an OR >1.00 indicates a higher odds of the outcome among mRNA-1273. P values for interactions: age = 0.014, sex = 0.612.
a
Overall analysis adjusted for sex, age, and history of any comorbidity, while the stratified analyses are adjusted for all variables except for the stratified variable.