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. 2022 Oct 26;18(10):e1010463. doi: 10.1371/journal.pgen.1010463

Fig 3. Functional analysis of DEK/NUP214 interacting complexes.

Fig 3

A. STRING analysis. The STRING algorithm identified 6 clusters of at least four interactors indicating their function as evidenced by different colors. B. MIST analysis of the protein complexes formed by DEK/NUP214 interactors and their function–threshold was set at a minimum of 4 interactors. C. IPA network analysis of DEK/NUP214 interactors shows the network with the lowest p-value, the "RNA damage and repair network," corresponding to 27 DEK/NUP214 interactors involved in this single network. Each node in the network represents a gene, and the solid or dotted lines connecting them show a direct or indirect association, respectively. Red/grey nodes were the input genes detected in this study; white nodes are molecules inserted by IPA from the Ingenuity Knowledge Base.