Table 3.

Univariate and multivariable logistic regression analyses of the risk factors associated with surgical recurrence

Variable	Univariate model			Multivariate model
	OR	95% CI	p-value	OR	95% CI	p-value
Age at surgery			0.0036			0.0000
G1	2.27	0.985–5.251		1.676	0.543–5.167
G2	2.44	1.367–4.373		2.299	1.054–5.012
G3	1.71	0.936–3.006		1.126	0.494–2.563
Gender, male	0.890	0.680–1.166	0.399
Age at diagnosis			0.0012
A1	1.71	0.865–3.379
A2	2.29	1.444–3.650
Disease location			0.0000			0.0009
L1	0.480	0.252–0.915		0.418	0.111–1.569
L2	1.854	0.912–3.769		1.902	0.497–7.281
L3	0.820	0.434–1.549		0.895	0.247–3.244
Disease behaviour
B1	1.039	0.659–1.634	0.986
B2	1.015	0.700–1.472
No history of perianal fistula	0.740	0.563–0.973	0.031
No history of perianal abscess	1.111	0.819–1.508	0.494
Smoke habit			0.557
No smokers	1.381	0.566–3.369
Smokers	1.568	0.673–3.655
No previous long-term use of steroids	0.564	0.415–0.766	0.0003
No previous long-term use of anti-TNFa	3.864	1.169–12.774	0.0085
No previous long-term use of ASA	0.59	0.429–0.811	0.0014

Long-term: > 6 months, before first surgery