Table 4.
Statistically different clinical characteristic in cumulative groups of patients below or over 40 years of age at first surgery
| G1 + G2 | G3 + G4 | P-value | |
|---|---|---|---|
| No. patients | 590 | 461 | |
| Age at surgery, median years (IQR) | 30 (24–35) | 50 (44–57) | |
| Smoking status at first surgery, n (%) | 0.0001 | ||
| Current | 207 (35.1) | 121 (26.2) | |
| Never | 330 (55.9) | 263 (57.0) | |
| Former | 12 (2.0) | 77 (16.7) | |
| Disease behaviour, n (%) | 0.0007 | ||
| B1 inflammatory | 139 (23.6) | 82 (17.8) | |
| B2 stricturing | 307 (52.0) | 294 (63.8) | |
| B3 penetrating | 144 (24.4) | 85 (18.4) | |
| Type of surgery, n (%) | 0.0189 | ||
| -Strictureplasty/ies | 62 (10.5) | 53 (11.5) | |
| -Ileocecal resection | 432 (73.2) | 326 (70.7) | |
| -Ileocecal resection + strictureplasty/ies | 29 (4.9) | 43 (9.3) | |
| -Other resections | 67 (11.4) | 39 (8.5) | |
| History of perianal abscess, n (%) | 185 (31.4) | 103 (22.3) | 0.0013 |
| History of perianal fistula, n (%) | 305 (51.7) | 196 (42.5) | 0.0034 |
| Surgical recurrence, n (%) | 188 (31.9) | 106 (23.0) | 0.0015 |
| Surgeries for recurrence, n (%) | 0.0023 | ||
| 0 | 402 (68.1) | 355 (77.0) | |
| 1 | 95 (16.1) | 63 (13.7) | |
| ≥ 2 | 93 (15.8) | 43 (9.3) | |
| Long-term treatment with anti-TNFα drugs before first surgery, n (%) | 11 (1.9) | 21 (4.6) | 0.0174 |
| Permanent end ileostomy | 2 (0.34%) | 6 (1.30%) | 0.1482 |
IQR interquartile range. Long-term: > 6 months, before first surgery