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. 2022 Nov 8;5:1198. doi: 10.1038/s42003-022-04128-8

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Mean CSF volume and CSF volumes of all patients before shunting until 15 months after shunting. b Mean brain volume and brain volumes of all patients before shunting until 15 months after shunting. c Mean ICP and ICPs of all patients before shunting until 15 months after shunting. d Mean force and forces in all patients before shunting until 15 months after shunting. It should be noted that the mean volumes, ICP, and force for healthy subjects also showed on the left side panels. The gray areas in statistical analysis tables show the stable areas of volumes, ICP, and fore changes. The CSF volume, brain volume, ICP, and forces values reached stable conditions 12, 15, 6, and 9 months after shunting, respectively. Since the differences between the values of these parameters in stable months were less than 1.0%. Hence, follow-up was stopped 15 months after shunting, and results were reported until the fifteenth month. Raw data for Fig. 2 is included in Supplementary Data 1. CSF cerebrospinal fluid, ICP intracranial pressure, SD standard deviation, SE standard error, CV coefficient of variation, CI confidence of interval.