Table 1.
Comparison of the results of the present study with the results of cine-PC MRI, experimental ICP, and previous studies. CSF volume means the volumes of SAS and ventricular system.
Parameters | Condition of subjects | Present study | Literature | ||||||
---|---|---|---|---|---|---|---|---|---|
FSI simulation | Experimental measurements | cine-PC MRI results | |||||||
Value | Source | Value | Source | Value | Source | Value | Source | ||
Maximum CSF velocity in cerebral aqueduct (cm/s) | Healthy subjects | 2.3 ± 0.1 | Supplementary Fig. 1 | — | — | 2.36 | Fig. 1f | 2.4 | 48 |
1.3 | 76 | ||||||||
Communicating hydrocephalus patients (pre-shunting) | 4.6 ± 0.4 | Supplementary Data 1 | — | — | 4.7 | Fig. 1f | 4.1 | 48 | |
3.5 | 76 | ||||||||
CSF volume (ml) | Healthy subjects | 116.3 ± 1.6 | Supplementary Fig. 2 | — | — | — | — | 129.3 | 48 |
118.6 | 76 | ||||||||
Communicating hydrocephalus patients (pre-shunting) | 412.8 ± 6.0 | Fig. 2a and Supplementary Data 1 | — | — | — | — | 410.2 | 48 | |
371.1 | 76 | ||||||||
Brain volume (ml) | Healthy subjects | 1213.3 ± 10.3 | Supplementary Fig. 3 | — | — | — | — | 1388.0 | 48 |
Communicating hydrocephalus patients (pre-shunting) | 1068.0 ± 19.8 | Fig. 2b and Supplementary Data 1 | — | — | — | — | 1120.3 | 48 | |
Maximum ICP (cm H2O) | Healthy subjects | 10.3 ± 0.2 | Supplementary Fig. 4 | — | — | — | — | >9.5 | 94 |
Communicating hydrocephalus patients (pre-shunting) | 29.5 ± 0.7 | Fig. 2c and Supplementary Data 1 | 28.9 | Fig. 1f and Supplementary Table 1 | — | — | 27.5 | 47 | |
26.8 | 48 | ||||||||
29.5 | 76 |