Table 2.

Linear regression analysis of variables associated with IgG antibody titre after BNT162b2.

	B	SE	Beta	P value
Age	− 0.021	0.001	− 0.399	< 0.001
Sex (base: male)	0.082	0.035	0.040	0.019
Date from 2nd vaccination	− 0.014	0.001	− 0.431	< 0.001
Interval between vaccinations (base: 21 day)
< 21 days	0.017	0.082	0.003	0.834
22–28 days	0.130	0.042	0.051	0.002
> 28 days	0.080	0.058	0.022	0.167
Smoking (base: none)	− 0.181	0.042	− 0.070	< 0.001
Alcohol (base: none)
Sometimes	− 0.040	0.038	− 0.017	0.300
Everyday	− 0.022	0.046	− 0.008	0.627
Daily medication (base: none)
Steroids	− 0.772	0.117	− 0.111	< 0.001
Immunosuppression	− 0.636	0.178	− 0.060	< 0.001
NSAIDs	− 0.045	0.061	− 0.012	0.459
Acetaminophen	0.001	0.108	0.000	0.990
Antihistamines	− 0.107	0.068	− 0.025	0.115
Comorbidities (base: none)
Hypertension	0.106	0.043	0.047	0.013
Diabetes	− 0.191	0.063	− 0.049	0.003
Heart disease	− 0.132	0.061	− 0.035	0.031
Kidney disease	− 0.209	0.150	− 0.022	0.162
Cancer	0.012	0.086	0.002	0.887
Connective tissue disease	− 0.285	0.123	− 0.040	0.021
Immune deficiency	0.051	0.307	0.003	0.869
Adverse reaction (base: none)
1	0.271	0.044	0.112	< 0.001
2≥	0.311	0.042	0.155	< 0.001

Connective tissue disease included Rheumatism.

Adverse reaction included whole body adverse reaction at 2nd dose (> 37.5 °C fever, fatigue, headache, joint pain, diarrhea, nausea, dizziness, and other).

NSAIDs, non-steroidal anti-inflammatory drugs.