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. 2022 Oct 25;13:1041616. doi: 10.3389/fendo.2022.1041616

Table 5.

Relationship between AST/ALT ratio and prediabetes in different sensitivity analyses.

Exposure Model I (HR,95%CI, P) Model II (HR,95%CI, P) Model III (HR,95%CI, P)
AST/ALT ratio 0.79 (0.73, 0.85) <0.0001 0.78 (0.73, 0.84) <0.0001 0.80 (0.75, 0.85) <0.0001
AST/ALT ratio (Quintile)
 Q1 Ref Ref Ref
 Q2 0.87 (0.80, 0.95) 0.0029 0.86 (0.81, 0.91) <0.0001 0.87 (0.81, 0.92) <0.0001
 Q3 0.82 (0.74, 0.89) <0.0001 0.85 (0.79, 0.91) <0.0001 0.85 (0.79, 0.91) <0.0001
 Q4 0.74 (0.67, 0.81) <0.0001 0.77 (0.71, 0.84) <0.0001 0.77 (0.71, 0.83) <0.0001
P for trend <0.0001 <0.0001 <0.0001

Model I was sensitivity analysis in participants without BMI≥24kg/m2. We adjusted gender, age, family history of diabetes, drinking status, smoking status, SBP, DBP, BMI, TC, TG, HDL-C, LDL-C, SCr, BUN, FPG.

Model II was sensitivity analysis in participants without age≥60 years. We adjusted gender, age, family history of diabetes, drinking status, smoking status, SBP, DBP, BMI, TC, TG, HDL-C, LDL-C, SCr, BUN, FPG.

Model III was sensitivity analysis in participants without drinker (current-drinker and ex-drinker). We adjusted gender, age, family history of diabetes, smoking status, SBP, DBP, BMI, TC, TG, HDL-C, LDL-C, SCr, BUN, FPG.

HR, hazard ratios; CI, confidence, Ref: reference; AST/ALT ratio: aspartate aminotransferase to alanine aminotransferase ratio.