Table 7.

Effect size of AST/ALT ratio on prediabetes in prespecified and exploratory subgroups.

Characteristic	No of participants	HR (95%CI) P value	P for interacion
Age, years			0.0605
<60	67934	0.82 (0.77, 0.87) <0.0001
≥60	7270	0.93 (0.83, 1.05) 0.2557
Gender			0.8142
Male	41909	0.81 (0.75, 0.87) <0.0001
Female	33295	0.80 (0.73, 0.87) <0.0001
BMI (kg/m2)			0.3382
< 24	47638	0.74 (0.69, 0.80) <0.0001
≥24	27566	0.79 (0.72, 0.85) <0.0001
SBP (mmHg)			0.4985
< 140	68621	0.80 (0.75, 0.85) <0.0001
≥140	6583	0.84 (0.73, 0.97) 0.0140
DBP (mmHg)			0.7741
<90	69882	0.79 (0.75, 0.84) <0.0001
≥90	5322	0.81 (0.69, 0.96) 0.0173
Smoking status			0.1505
Current smoker	11788	0.84 (0.73, 0.96) 0.0133
Ever smoker	2918	0.61 (0.45, 0.82) 0.0012
Never smoker	60498	0.80 (0.75, 0.85) <0.0001
Drinking status			0.5173
Current drinker	1579	0.88 (0.64, 1.20) 0.4163
Ever drinker	11307	0.74 (0.64, 0.86) <0.0001
Never drinker	62318	0.80 (0.75, 0.85) <0.0001
Family history of diabetes			0.3478
No	73750	0.79 (0.75, 0.84) <0.0001
Yes	1454	0.64 (0.42, 1.00) 0.0480

Above model adjusted for gender, age, family history of diabetes, drinking status, smoking status, SBP, DBP, BMI, TC, TG, HDL-C, LDL-C, SCr, BUN, FPG.

In each case, the model is not adjusted for the stratification variable.