Fig. 2.

Dual-mode imaging (PAI combined with FI). The NIR-II fluorescence images (A) of epidermal growth factor receptor (EGFR)-positive FTC-133 tumor-bearing mice were captured before injection and 1, 4, 24, and 48 ​h after tail vein injection of Affibody-DAPs, respectively. The blocking group was co-injected with Affibody ZEGFR:1904 and Affibody-DAPs. (Images of both groups using the same acquisition parameters.) Coronal views of the 3D volume rendering of the PAI (B) of the FTC-133 tumors were obtained at the predefined time intervals right after FI. White dashed lines and white arrows indicate tumors [25] (Reproduced from Ref. [25] with permission. Copyright 2017 American Chemical Society).