| Bevacizumab (antibody) and IR825 [52] |
The treatment efficiency of tumor eradication by near infrared (NIR) laser irradiation was significantly improved. |
Build a sequentially targeted nanoplatform (IR825@Bev-PLGA-PFPNPs) for PTT. |
ATC |
| mesoporous polydopamine nanoparticles (MPDA) [53] |
Porous nanoparticles show huge advantages in the field of drug delivery, which can effectively improve the loadings of chemotherapeutic drugs or other substances. |
MPSNs were used as nanocarriers for loading various drug molecules by virtue of their open pore structure and adjustable pore channels to treat cancer. |
ATC |
| the131l-labeled BSA-modified CuS nanoparticles (131I-BSA@CuS) [54] |
The synthesized nanomaterial showed uniform dispersion, good stability and aqueous solubility, excellent photothermal properties, and long-term retention in ATC. |
As a therapeutic agent, it has shown remarkable efficacy in both ACT radiotherapy and PTT. |
ATC |
| B–OMe-NPs [55] |
B–OMe-NPs and laser irradiation mediated therapy and cell proliferation inhibition lead to tumor tissue damage |
It has good photostability and effective photoacoustic imaging and fluorescence imaging ability, and combines PTT and PDT treatment modes |
Cancer |
| Based on a polypyrrole (Ppy)-poly- (Ethylene imine)-siILK nanocomplex (PPRILK) [56] |
Tumors were completely eradicated by photothermal therapy, and the recurrences and metastases were obviously restrained by siILK |
It has excellent biocompatibility and stability, and can be modified by surface to achieve charge reversal to load and release siILK under appropriate conditions. |
PTC |
| holo-TRANSFERRIN, (EGF and lapatinib-functionalized AuNPs (gold nanoparticles) [57] |
AuNPs have many advantages, including efficient light-heat conversion and tunable optical properties that can be manipulated by varying the AuNPs's physical characteristics such as size and shape. |
For PTT, nanotechnology can change the photothermal properties of the medium and enhance tumor hyperthermia. |
ATC |
| Photo-triggered Gold nanodots capped mesoporous silica nanoparticles Au@MSNs [58] |
The capsaicin and Cap-AuMSNs were able to inhibit the migration and invasion of cancer cells. |
For PTT, Cap-AuMSNs are in the nano regime and highly stable. |
TC |
