TABLE 1.
Strain | Source (year of isolation) | Isolate type (location) | Sero-group | Sero(sub)type | Clustera | Reactivity with MAbb:
|
Refer-ence | |||
---|---|---|---|---|---|---|---|---|---|---|
9-2-L379 | B306 | 4B12/C11 | SM1 | |||||||
B1940 | U. Berger (?) | Clinical (Germany) | B | NT:P1.3,6,15 | — | + | + | + | + | 9 |
MC58 | E. R. Moxon (1985) | Clinical (United Kingdom) | B | 15:P1.17,16b | ET-5 complex | + | + | + | + | 5 |
2120 | Our clinical isolate (1997) | Clinical (Germany) | C | NT:P1.2,5 | ET-37 complex | + | − | + | − | 29 |
ET, electrophoretic type; —, the ET of strain B1940 does not correspond to any well-known clone associated with a high incidence of disease.
Reactivities with MAbs were determined by indirect immunofluorescence (for 9-2-L379) and by Western blot analysis (for B306, 4B12/C11, and SM1). 9-2-L379 is reactive with LPS of immunotype L3,7,9 and was kindly provided by W. D. Zollinger (Washington, D.C.); B306 and 4B12/C11 bind to meningococcal Opc and Opa, respectively, and were provided by M. Achtman (Berlin, Germany); and SM1 binds to neisserial pilin of class I pili (donation of M. Virji, Bristol, United Kingdom).