TABLE 4.
Shrunk coefficients after LASSO analysis for predicting plasma TG change after 1.8 g/day EPA + DHA.
| Variable name | Mean-centered coefficient (SD) | Standardized coefficient |
| Intercept | −0.330 (0.103) | 0 |
| APOE—APOE4 variant | −0.010 (0.006) | |
| Baseline BMI (kg/m2) | 0.002 (0.001) | 0.017 |
| Baseline CRP (mg/l) | 0.005 (0.002) | 0.030 |
| Baseline plasma insulin (mmol/L) | 0.014 (0.003) | 0.118 |
| Baseline IL-10 (pg/ml) | −0.007 (0.002) | −0.045 |
| Baseline VCAM-1 (ng/ml) | <−0.001 | −0.030 |
| Pre-intervention plasma TG (mmol/L) | −0.442 (0.048) | −0.577 |
| Pre-intervention LDL-cholesterol (mmol/L) | 0.035 (0.006) | 0.066 |
| Fruit consumption (g) | <0.001 | −0.011 |
| Saturated fat consumption (g) | 0.001 (0.001) | 0.040 |
| rs320 (G > T) | −0.015 (0.004) | |
| rs2250656 (C > T) | −0.017 (0.009) | |
| rs1800588 (T > C) | 0.058 (0.031) | |
| rs1800795 (C > G) | 0.024 (0.012) | |
| rs1800896 (C > T) | 0.015 (0.009) | |
| rs5370 (T > G) | 0.054 (0.030) | |
| C20:3n-6 | 0.027 (0.012) | 0.049 |
| C20:4n-6 | 0.006 (0.002) | 0.024 |
Variables listed were selected by 3 or more of the 5 imputed datasets, and depict the mean (SD) of their shrunk coefficients across all imputed datasets for which they were selected. Both mean-centered (left) and standardized (right, variables on continuous numeric scale only) shrunk coefficients are presented. APOE/APOE4, apolipoprotein E3/E4 or E4/E4; CRP, C-reactive protein; IL-10, interleukin 10; LDL, low-density lipoprotein; TG, triglyceride; VCAM-1, vascular cell adhesion protein 1.