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. 2022 Oct 25;9:989716. doi: 10.3389/fnut.2022.989716

TABLE 6.

Model output after performing backward stepwise regression for predicting plasma PC EPA + DHA change after 1.8 g/day EPA + DHA.

Pooled mean centered regression coefficients
Standardized regression coefficients, un-imputed dataset
Term Estimate Std. error Test statistic p Term Estimate Std. error Test statistic p
Intercept 3.915 0.193 20.27 0 Intercept 4.235 0.157 26.95 <0.001
Age 0.043 0.009 4.777 <0.001 Age 0.563 0.115 4.897 <0.001
Sex—Female 0.799 0.224 3.572 <0.001 Sex—Female 0.774 0.224 3.451 0.001
BMI −0.088 0.035 −2.537 0.012 BMI −0.320 0.118 −2.716 0.007
rs2241883—T/C 0.564 0.229 2.462 0.014 rs2241883 (T > C) 0.323 0.107 3.012 0.003
rs2241883—C/C 0.806 0.343 2.350 0.019
C16:0 −0.429 0.109 −3.922 <0.001 C16:0 −0.844 0.219 −3.852 <0.001
C18:0 −0.281 0.109 −2.572 0.011 C18:0 −0.496 0.197 −2.515 0.012
C18:1n-7 −0.350 0.120 −2.904 0.004 C18:1n-7 −0.488 0.173 −2.813 0.005
C18:2n-6 −0.454 0.091 −5.009 <0.001 C18:2n-6 −1.304 0.263 −4.966 <0.001
C20:4n-6 −0.491 0.111 −4.408 <0.001 C20:4n-6 −0.903 0.211 −4.287 <0.001
C20:5n-3 −1.670 0.202 −8.275 <0.001 C20:5n-3 −1.337 0.163 −8.217 <0.001
C22:6n-3 −0.548 0.112 −4.882 <0.001 C22:6n-3 −0.702 0.142 −4.935 <0.001

Data showing mean-centered regression coefficients pooled across all imputed datasets (left), and upon applying the model to the standardized un-imputed dataset (right, continuous numeric scale variables standardized only).