Table 1.
Clinical features and evaluation of clinical relevance of B. cereus-group isolates. Names of isolates identified genomically as B. anthracis are shown in bold. The isolate name identified as B. basilensis sp. nov. is shown in italics. ID, identification; PICC, peripherally inserted central venous catheter; NA, not available; MRSA, Methicillin-resistant Staphylococcus aureus; dd, differential diagnosis; GVHD, graft versus host disease; Age groups: 1, <18years; 2, 18-50years; 3, >50years; Amounts: +, low; ++, moderate; +++, numerous; CFU, colony-forming unit. Detailed case reports of selected isolates are given in the supplementary material.
| Sample number | Age group | Date of collection | Material | Localization | Culture result (amount) | Infectious disease consultation interpretation | Clinical relevance of B. cereus-group |
|---|---|---|---|---|---|---|---|
| 128633-19 | 2 | 07/19 | Blood | Not known | B. cereus-group | Bacteremia (1/6 bottles positive), dd spondylodiscitis | Relevant |
| 607738-19 | 3 | 07/19 | Swab | Lower leg | B. cereus-group (2 CFU), Enterococcus faecalis (++) | Soft tissue infection after compartment lower leg (E. faecalis) | Not relevant |
| 130277-19 | 2 | 07/19 | Blood | Venous catheter | Staphylococcus hominis, B. cereus-group | Polymicrobial Hickman Catheter infection (3/4 bottles positive) | Relevant |
| 607730-19 | 2 | 07/19 | Biopsy | Upper leg | B. cereus-group (+), Streptococcus constellatus (+), S. aureus (1 CFU), Haemophilus parainfluenzae (+), Prevotella denticola (+) | Colonization of wound | Not relevant |
| 130415-19 | 3 | 07/19 | Blood | Venous peripher | B. cereus-group | Contamination (1/4 bottles positive) | Not relevant |
| 608121-20 | 2 | 08/20 | Swab | Finger | Kocuria spp. (1 CFU), B. cereus-group (+) | Soft tissue and bone infection | Relevant |
| 804229-21 | 1 | 09/21 | Swab | Nose | B. cereus-group (+) | Postnatal adaption disorder, pneumonitis, screening for MRSA | Not relevant |
| 607095-21 | 3 | 07/21 | Biopsy | Lower leg | E. faecalis (+++), B. cereus-group (++) | Soft tissue infection after compartment lower leg (E. faecalis, B. cereus-group) | Relevant |
| 203778-21 | 2 | 08/21 | Swab | Vaginal | B. cereus-group (1 CFU), vaginal flora (+++), gram labile rods (morphotype gardnarella) (+++) | NA | Not relevant |
| 402914-21 | 1 | 08/21 | Swab | Skin abdomen | Skin flora (+), B. cereus-group (1 CFU) | Common B-cell acute lymphoblastic leukemia; stem cell transplantation; facial herpes zoster | Not relevant |
| 129606-21 | 3 | 08/21 | Blood | PICC line | B. cereus-group | Contamination (1/4 bottles positive) | Not relevant |
| 607632-21 | 3 | 08/21 | Biopsy | Lower leg | E. faecalis (+), B. cereus-group (+) | Soft tissue infection after compartment lower leg (E. faecalis, B. cereus-group) | Relevant |
| 403206-21 | 3 | 08/21 | Swab | Cheeks | B. cereus-group (+++), Mixta calida (+++), S. aureus (++), S. hominis (++) | Superficial swab for dermatitis | Not relevant |
| 403291-21 | 2 | 09/21 | Swab | Abdomen | S. aureus (+), B. cereus-group (1 CFU) | Abscess/skin infection with S. aureus | Not relevant |
| 403507-21 | 3 | 09/21 | Swab | Lower arm | B. cereus-group (+) | Colonization of wound | Not relevant |
| 135455-21 | 3 | 09/21 | Blodd | PICC line | B. cereus-group | Polymicrobial catheter infection/dd enteritis with GVHD | Relevant |