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. 2022 Oct;11(10):3610–3619. doi: 10.21037/tcr-22-589

Table 4. Gene set enrichment analysis of The Cancer Genome Atlas colon cancer with the MFN2 high expression and low expression by using KEGG pathway gene sets.

Name ES NES NOM P value FDR q-value
MFN2 high-expression
   KEGG_GALACTOSE_METABOLISM 0.76 2.32 <0.001 <0.001
   KEGG_GLYCOLYSIS_GLUCONEOGENESIS 0.68 2.21 <0.001 0.002
   KEGG_VEGF_SIGNALING_PATHWAY 0.54 2.11 <0.001 0.006
   KEGG_APOPTOSIS 0.53 1.98 0.002 0.010
MFN2 low-expression
   KEGG_RIBOSOME −0.83 −1.81 0.016 0.137

MFN2, mitofusin 2; KEGG, Kyoto Encyclopedia of Genes and Genomes; ES, enrichment score; NES, normalized enrichment score; NOM, normal; FDR, false discovery rate.