Table 3. Chi-square analysis of the association between MAN2A1 expression value and clinicopathologic characteristics of CRC patients in TCGA database.

Variables	Total	Low expression	High expression	χ2	P
Age, years				0.902	0.342
<65	249	127	122
≥65	368	202	166
Gender				0.772	0.380
Female	288	159	129
Male	329	170	159
Radiation treatment				1.970	0.160
Yes	128	72	56
No	393	193	200
Pharmacological treatment				0.835	0.361
Yes	124	66	58
No	395	195	200
TNM stage				5.426	0.02*
Stage I	105	55	50
Stage II	226	108	118
Stage III	179	101	78
Stage IV	88	56	32
Invasion depth				0.012	0.914
T1	20	10	10
T2	105	57	48
T3	420	228	192
T4	70	32	38
Lymph node metastasis				3.827	0.05*
Yes	264	153	111
No	350	175	175
Distant metastasis				3.640	0.056
Yes	88	56	32
No	464	244	220

*, P<0.05. CRC, colorectal cancer; TCGA, The Cancer Genome Atlas.