Table 5. Signaling pathways enriched in the MAN2A1 high-expression group.

Signaling pathway	NES	NOM p-value	FDR q-value
KEGG_wnt signaling pathway	2.361	≤0.001	0.003
KEGG_long term potentiation	2.328	≤0.001	0.001
KEGG_oocyte meiosis	2.296	≤0.001	9.30E-04
KEGG_ubiquitin mediated proteolysis	2.281	≤0.001	6.98E-04
KEGG_neurotrophin signaling pathway	2.259	≤0.001	0.001
KEGG_GNRH signaling pathway	2.228	≤0.001	0.001
KEGG_progesterone mediated oocyte maturation	2.223	≤0.001	9.62E-04
KEGG_colorectal cancer	2.223	≤0.001	8.42E-04
KEGG_pathways in cancer	2.211	≤0.001	7.48E-04
KEGG_prostate cancer	2.201	≤0.001	6.73E-04
KEGG_TGF beta signaling pathway	2.195	≤0.001	6.12E-04
KEGG_lysine degradation	2.193	≤0.001	5.61E-04
KEGG_MAPK signaling pathway	2.184	≤0.001	5.18E-04
KEGG_ERBB signaling pathway	2.176	≤0.001	7.73E-04
KEGG_apoptosis	2.176	≤0.001	7.22E-04
KEGG_melanogenesis	2.174	≤0.001	7.41E-04
KEGG_butanoate metabolism	2.171	≤0.001	6.97E-04
KEGG_phosphatidylinositol signaling system	2.171	≤0.001	6.58E-04
KEGG_P53 signaling pathway	2.169	≤0.001	6.24E-04
KEGG_beta alanine metabolism	2.161	≤0.001	7.03E-04

NES, normalized enrichment score; NOM, nominal; FDR, false discovery rate.