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. 2022 Oct 28;8(11):e11278. doi: 10.1016/j.heliyon.2022.e11278

Table 2.

List of P-gp and CYP3A4 substrates, inhibitors and inducers observed in prescriptions.

Inducers Inhibitors Substrates
P-GP
Aspirin Atorvastatin Clopidogrel
Diltiazem Metformin Pantoprazole
Spironolactone Pioglitazone Omeprazole
Carvedilol Losartan
Diltiazem Digoxin
Sodium valproate Amitriptyline
Pantoprazole Teneligliptin
Omeprazole Propranolol
Carvedilol
Acetaminophen
CYP3A4
Phenytoin Amlodipine Atorvastatin
Losartan
Amitriptyline
Clopidogrel
Phenytoin
Amlodipine

With reference to P-gp and CYP3A4 substrates, inducers and inhibitors previously reported [15, 29].