Table 3.
Cox regression analysis of PFS
| Variables | Univariate Analysis | Multivariate Analysis | ||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| HR | 95% CI | P | HR | 95% CI | P | |
| Age (years) | ||||||
| <52 | 1 | |||||
| ≥52 | 0.86 | 0.56-1.33 | 0.497 | |||
| Gender | ||||||
| Male | 1 | |||||
| Female | 0.66 | 0.4-1.09 | 0.107 | |||
| Pathology | ||||||
| Non-keratinizing | 1 | |||||
| Keratinized | 92.69 | 5.77-1488.4 | 0.001 | 43.05 | 2.67-695.38 | 0.008 |
| Undifferentiated | 2.7 | 1.15-6.33 | 0.022 | 1.73 | 0.68-4.35 | 0.248 |
| Adenoid cystic | 1.97 | 0.27-14.46 | 0.504 | 1.09 | 0.1-11.6 | 0.946 |
| Clinical stage | ||||||
| III | 1 | |||||
| IVa | 5.58 | 3.13-9.96 | <0.001 | 5.54 | 2.29-13.4 | <0.001 |
| T staging | ||||||
| T1-2 | 1 | |||||
| T3-4 | 1.45 | 0.93-2.28 | 0.101 | |||
| N staging | ||||||
| N1 | 1 | |||||
| N2 | 0.78 | 0.3-2.04 | 0.619 | 0.58 | 0.19-1.73 | 0.326 |
| N3 | 2.87 | 1.11-7.4 | 0.029 | 0.69 | 0.19-2.6 | 0.589 |
| ECOG socre | ||||||
| 0 | 1 | |||||
| 1 | 0.8 | 0.47-1.34 | 0.393 | |||
| Group | ||||||
| Control | 1 | |||||
| Experimental | 0.64 | 0.41-0.99 | 0.045 | 0.53 | 0.34-0.84 | 0.006 |