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IVM inhibited the metastasis of HCT-8 cells-derived tumor in vivo
| Doses of (mg/kg) | ||||
|---|---|---|---|---|
|
| ||||
| 0.0 | 1.0 | 2.0 | 3.0 | |
| Formation of metastasis tumors (%) | 100 | 50 | 33.3 | 16.7 |
| Volume of the tumor nodules (mm3) | 2410.6 | 730.5 | 249.5 | 125.0 |
| Numbers of the tumor nodules | 16 | 8 | 2 | 1 |
| Thoracic cavity | 1 | 0 | 0 | 0 |
| Kidneys | 1 | 0 | 0 | 0 |
| Lungs | 0 | 2 | 0 | 0 |
| Duodenum | 1 | 0 | 0 | 0 |
| Mesentery | 3 | 0 | 0 | 0 |
| Eyes | 0 | 1 | 0 | 0 |
| Muscle | 10 | 5 | 2 | 1 |
