Table 5.
Groups | Observation (day) | ||
---|---|---|---|
| |||
0 | 7th | 21st | |
AST (u/L) | |||
Control | 81 ± 6.1 | 75 ± 4.3 | 69 ± 5.1 |
SVP | 63 ± 5.5 | 180 ± 11* | 171 ± 6.4* |
SVP + Jma | 71 ± 7.8 | 137 ± 11& | 140 ± 5.6& |
SVP + Jmb | 69 ± 8.4 | 25 ± 12# | 116 ± 6.0# |
ALT (u/L) | |||
Control | 30 ± 4.3 | 41 ± 6.2 | 35 ± 3.5 |
SVP | 28 ± 3.5 | 98 ± 4.9* | 97 ± 8.9* |
SVP + Jma | 23 ± 3.6 | 74 ± 6.3& | 70 ± 4.2& |
SVP + Jmb | 30 ± 3.0 | 60 ± 6.9# | 58 ± 6.0# |
Mean ± SEM (n=6), where SVP is sodium valproate (500 mg/kg i.p), SVP + Jma is sodium valproate + Jatropha mollissima extract (200 mg/kg/21 days), SVP + Jmb is sodium valproate + Jatropha mollissima extract (400 mg/kg/21 days).
Indicates P < 0.05 vs normal.
P < 0.05 shows vs SVP.
P < 0.05 Indicates SVP + Jatropha mollissima on corresponding days.