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. 2022 Oct 3;149(19):dev200986. doi: 10.1242/dev.200986

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© 2022. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 1. — ClueGO analysis of differentially expressed transcripts in MAPK/ERK-deficient nephron progenitors. (A,B) Overview pie chart of cellular component and KEGG pathway analyses of the (A) total and (B) downregulated differentially expressed genes (DEGs) between control and MAPK/ERK-deficient NPs. The percentage of genes per term is shown in each group. GO analysis was performed using the Cytoscape plugin ClueGO. The pie chart shows the enriched signaling pathway categories based on the κ coefficient of 0.5. Significantly enriched GO terms are indicate by **P<0.001.