TABLE 2.
Murine splenocyte proliferation and SI in response to Thio-SODa
| Vaccine and dose (CFU) | Proliferative response to Thio-SOD at the following concn (μg/well):
|
|||
|---|---|---|---|---|
| 0 | 0.016 | 0.08 | 0.4 | |
| Saline | 1,200 | 2,060 (1.7) | 2,050 (1.7) | 2,100 (1.8) |
| B. abortus RB51, 2 × 108 | 1,053 | 2,883 (2.7) | 3,848 (3.6) | 8,864 (8.4) |
| E. coli(pBSSOD), 1 × 106 | 2,189 | 4,305 (2.0) | 9,125 (4.2) | 23,029 (10.5) |
| E. coli(pBS), 1 × 106 | 2,300 | 3,598 (1.6) | 3,038 (1.3) | 9,272 (4.0) |
a
Splenocytes were cultured at 4 × 105 cells per well 5 weeks postimmunization. Each value is the average counts per minute of triplicate cultures of cells obtained from a pool of five mice in each group. Numbers in parentheses are the SIs for each group.