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A simplified diagram of brain reward circuitry. a A simplified schematic of the glutamatergic and GABAergic projections to the VTA (Charara et al. 1996; Kalivas et al. 1993; Omelchenko and Sesack 2006; Sesack et al. 2003; Sesack and Pickel 1992). b Some sites of nAChR expression within the mesoaccumbens dopaminergic circuitry. The cellular localization and functional role of nAChRs within PMT are currently unknown
