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. 2022 Nov 7;17:176. doi: 10.1186/s13014-022-02147-7

Table 1.

Clinical characteristics of study participants

Characteristic No. patients Percentage
Total 259 100
Sex
 Male 194 74.9
 Female 65 25.1
Median age (range); years 49 (19–74)
T category
 T 1–2 34 13.1
 T 3–4 225 86.9
N category
 N 0–1 89 34.4
 N 2–3 170 65.6
Stage
 III 129 49.8
 IVA 130 50.2
Plasma EBV-DNA (copies/mL)
 ≤ 500 173 66.8
 > 500 86 33.2
95% of target volume received dose greater than (D95, Gy)
 Average dose of nasopharynx (PTVnx + rn) (range) 70.2 (66.1–74.3)
 Average dose of neck node (PTVnd) (range) 69.4 (60.7–75.9)
Sites of residual
 Primary focus 121 46.7
 Retropharyngeal lymph nodes 54 20.8
 Cervical lymph nodes 152 58.7
Median time to boost after RT (range); days 36 (1–74)
Average boost dose for primary focus (range); Gy 8.1 (4–12.5)
Average boost dose for retropharyngeal lymph nodes (range); Gy 8.3 (5–12.5)
Average boost dose for cervical lymph nodes (range); Gy 8.6 (4–18)

EBV-DNA Epstein-Barr virus-deoxyribonucleic acid, PTVnx + rn planning gross target volume of the nasopharyngeal and retropharyngeal lymph node, PTVnd planning gross target volume of the cervical lymph nodes, RT radiotherapy