Table 1.
Baseline characteristics of participants according to NT-ProBNP levels
| NT-ProBNP (pg/ml) | ||||
|---|---|---|---|---|
| Variable | < 100 | 100–299 | ≥ 300 | Total |
| Age (years) | 55.1 (0.2) | 61.8 (0.4) | 66.3 (0.6) | 57.4 (0.2) |
| Age category (%) | ||||
| 45–59 | 73.2 (1.0) | 42.1 (1.8) | 24.5 (2.4) | 62.5 (1.1) |
| 60–79 | 26.8 (1.0) | 57.9 (1.8) | 75.5 (2.4) | 37.5 (1.1) |
| Male (%) | 53.0 (1.0) | 26.5 (1.2) | 36.3 (2.8) | 45.5 (0.7) |
| Race-ethnicity (%) | ||||
| Non-Hispanic White | 75.3 (1.9) | 81.5 (2.0) | 81.4 (2.8) | 77.2 (1.8) |
| Hispanic | 10.1 (1.7) | 8.1 (1.5) | 7.8 (2.0) | 9.5 (1.6) |
| Non-Hispanic Black | 9.9 (1.0) | 7.3 (1.0) | 9.6 (1.7) | 9.3 (0.9) |
| Other | 4.7 (0.7) | 3.0 (0.7) | 1.2 (0.6) | 4.0 (0.6) |
| BMI (kg/m2) | 28.9 (0.1) | 28.1 (0.2) | 28.5 (0.5) | 28.6 (0.1) |
| SBP (mmHg) | 127.2 (0.3) | 135.0 (0.8) | 143.6 (1.5) | 130.2 (0.3) |
| DBP (mmHg) | 75.6 (0.2) | 72.6 (0.4) | 72.9 (0.8) | 74.7 (0.2) |
| Triglycerides (mg/dL) | 156.5 (3.1) | 132.4 (2.6) | 146.1 (5.3) | 150.0 (2.3) |
| HbA1c (%) | 5.7 (0.0) | 5.6 (0.0) | 5.7 (0.1) | 5.6 (0.0) |
| HDL-C (mg/dL) | 52.3 (0.3) | 58.0 (0.6) | 56.5 (1.2) | 53.9 (0.3) |
| AST (U/L) | 25.8 (0.3) | 24.0 (0.5) | 25.5 (0.7) | 25.3 (0.2) |
| ALT (U/L) | 27.4 (0.4) | 21.9 (0.6) | 22.5 (1.1) | 25.8 (0.3) |
| eGFR (ml/min/1.73 m2) | 91.5 (0.3) | 85.0 (0.6) | 73.2 (1.4) | 88.8 (0.3) |
| Total Cholesterol (mg/dl) | 212.1 (0.8) | 209.2 (1.3) | 206.6 (2.7) | 211.0 (0.7) |
| Blood pressure (%) | ||||
| Optimal | 24.9 (1.1) | 19.5 (1.3) | 7.8 (1.9) | 22.5 (0.9) |
| Normal | 20.1 (0.9) | 12.7 (1.1) | 8.9 (1.9) | 17.6 (0.7) |
| High-normal | 13.6 (0.6) | 12.2 (1.2) | 10.9 (1.9) | 13.1 (0.5) |
| Hypertension | 41.4 (1.4) | 55.6 (1.6) | 72.3 (2.3) | 46.9 (1.2) |
| Education (%) | ||||
| High school or less | 43.0 (1.4) | 49.2 (1.9) | 62.8 (3.9) | 45.8 (1.3) |
| Some college | 29.8 (1.0) | 27.1 (1.7) | 19.9 (2.4) | 28.5 (0.9) |
| College graduate or above | 27.2 (1.4) | 23.7 (1.8) | 17.3 (3.1) | 25.7 (1.2) |
| Glycemic category (%) | ||||
| Euglycemic | 70.0 (1.4) | 69.9 (2.1) | 58.6 (2.0) | 69.0 (1.2) |
| Pre-diabetes | 17.7 (1.0) | 16.9 (1.7) | 18.9 (1.7) | 17.6 (0.8) |
| Diabetes | 12.3 (0.7) | 13.1 (1.1) | 22.5 (1.9) | 13.4 (0.6) |
| UACR (mg/g, %) | ||||
| < 30 | 92.0 (0.6) | 87.8 (1.3) | 66.1 (2.6) | 89.4 (0.6) |
| 30–300 | 7.3 (0.5) | 10.8 (1.2) | 25.3 (2.4) | 9.3 (0.5) |
| > 300 | 0.7 (0.2) | 1.4 (0.3) | 8.6 (1.3) | 1.4 (0.2) |
| Cigarette smoke (%) | ||||
| Never | 44.9 (1.2) | 49.6 (1.7) | 42.0 (2.6) | 45.8 (1.0) |
| Former | 34.4 (1.0) | 31.7 (1.7) | 40.2 (2.6) | 34.1 (1.0) |
| Current | 20.7 (0.9) | 18.8 (1.4) | 17.7 (2.1) | 20.1 (0.8) |
Data are expressed as weighted proportions (Standard Error (SE)) for categorical variables and as weighted means (SE) for continuous variables
BMI Body Mass Index, CKD chronic kidney disease, CVD cardiovascular disease, UACR urinary albumin creatinine ratio, HbA1c Hemoglobin A1c, HDL high density lipoprotein, SBP systolic blood pressure, DBP diastolic blood pressure