Table 3.

Cox-proportional hazard model evaluating the association between NT-ProBNP levels and all-cause mortality according to baseline HbA1c levels

Population	NT-ProBNP (pg/ml)	All-cause mortality
		HR	95% CI	p-value
Whole population	Per 1 SD	1.11	1.07–1.17	< 0.001
	< 100	1.00	Ref.
	100–299	1.61	1.12–2.32	0.012
	≥ 300	2.96	1.75–5.00	< 0.001
HbA1c < 5.7%	Per 1 SD	1.12	1.07–1.18	< 0.001
	< 100	1.00	Ref.
	100–299	1.72	1.00–2.95	0.050
	≥ 300	3.12	1.50–6.49	0.003
HbA1c 5.7–6.4%	Per 1 SD	1.23	1.05–1.43	0.010
	< 100	1.00	Ref.
	100–299	1.84	0.92–3.67	0.082
	≥ 300	3.79	1.59–9.01	0.003
Diabetes	Per 1 SD	1.10	1.05–1.16	< 0.001
	< 100	1.00	Ref.
	100–299	1.44	0.81–2.56	0.206
	≥ 300	2.43	0.98–6.06	0.056

Covariates included in model were age, sex, race-ethnicity, body mass index, education, cigarette smoke, total cholesterol, eGFR, blood pressure category, prevalent cardiovascular disease and alcohol consumption

CI confidence interval, NT-ProBNP N-terminal pro-B natriuretic peptide