Table 2.

Description of the standard physicochemical properties employed for the models training

Physicochemical property	Abbreviated representation in pfeature	Description
Positively charged	PCP_PC	A measure of the residual positive charge resident on an octapeptide
Negatively charged	PCP_NC	A measure of the residual negative charge on an octapeptide
Neutral towards water	PCP_NE	Answers the question, how neutral is the octapeptide towards water
Polarity	PCP_PO	A measure of how polar an octapeptide is
Non-polarity	PCP_NP	A measure of how non-polar an octapeptide is
Aliphaticity	PCP_AL	Gives the measure of how aliphatic the octapeptide is
Cyclicity	PCP_CY	Gives a measure of how many cyclic rings are present in an octapeptide
Aromaticity	PCP_AR	Answers the question, how aromatic is the octapeptide?
Acidity	PCP_AC	Gives a measure of how acidic an octapeptide is
Basicity	PCP_BS	Gives the measure of how basic an octapeptide is
Neutral pH	PCP_NE_pH	Measures the pH of an octapeptide under neutral condition
Hydrophilicity	PCP_HB	Measures the tendency of water to include non-polar molecules
Hydrophobicity	PCP_HL	Measures the tendency of water to exclude non-polar molecules
Sulfur Content	PCP_SC	Gives the proportion of Sulfur in an octapeptide