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. 1999 Mar;67(3):1011–1017. doi: 10.1128/iai.67.3.1011-1017.1999

TABLE 1.

Effects of chemical inhibitors on the phagocytosis of S. typhimurium by BAC-1.2F5 cells

Pretreatment of cells Phagocytosis (%) ± SD
None 100
Toxin B
 10 ng/ml 56 ± 9.0
 100 ng/ml 5 ± 4.0
Wortmannin (100 ng/ml) 3 ± 1.5
Cytochalasin B (10 μM) 2 ± 1.0

Macrophages were infected with Salmonella (MOI of 25). Phagocytosis was assessed as described in Materials and Methods. Untreated macrophages phagocytosed 55% (± 11) of the original inoculum. The phagocytic activity of untreated macrophages was set as 100%.